Quality survey on efficacy of carboxytherapy for localized lipolysis

Georgia S. K. Lee, MBBS, MD

Journal of Cosmetic Dermatology, 15, 484-492



 Background: A survey was conducted to ascertain the efficacy of carboxytherapy for localized lipolysis.

Methods Patients on physical, dietary, or drug concurrent therapy were excluded. Paired measurements (initial versus 8th course) between treated (right) and untreated (left) sides were compared for braline, upper arm, abdomen, and thigh.

Results Ten women, age range 23–37 years, were reviewed. Weight and body mass index were unchanged. Significant reductions (P < 0.01) were obtained for braline and abdominal caliper and ultrasound measurements. Mean (SD) decreases in caliper braline and abdomen measurements were 6.9 (5.9) and 4.3 (3.0) mm, respectively. Mean (SD) changes in ultrasound abdominal readings were  6.6 (3.8),  7.4 (3.2), and  6.8 (3.5) mm for upper, lower, and flank, respectively.

Limb girth measurements were significant for the thigh ( 1.3 [0.8] mm) but not for the upper limb.

Conclusion These results are in agreement with those reported originally and demonstrate that carboxytherapy is locally effective in reduction of subcutaneous fat. The results are in agreement with those reported previ- ously in the same setting and recognized that car- boxytherapy is safe and effective within treatment guidelines. The localized effect on adiposities has been quantified in a comparative setting and explains the clinical usefulness of CO2 therapy in treating skin irregularity and as a complement to liposuction.