Profhilo Structura: The New Innovation in Facial Aesthetics

Sebastiano Accaputo
June 5, 2024


Profhilo Structura is the latest breakthrough in the world of facial aesthetics, offering an advanced solution to restore lost facial volume and contours. Developed by IBSA Derma, this innovative injectable combines high and low molecular weight hyaluronic acid using the proprietary NAHYCO® Hybrid Technology. It represents a new generation of the renowned Profhilo treatment,specifically designed to target and regenerate superficial facial fat,providing natural and long-lasting results.

What is Profhilo Structura?

Profhilo Structura is formulated with 45 mg of low molecular weight hyaluronic acid and 45 mg of high molecular weight hyaluronic acid in a 2 mL syringe. Unlike other hyaluronic acid fillers, it utilizes NAHYCO® Hybrid Technology, which enhances its ability to restore facial volume and contours without the use of chemically cross-linked molecules. This results in a more natural appearance compared to traditional dermal fillers.

Uses of Profhilo Structura

Primarily used for the face, Profhilo Structura is effective in reconstructing and reorienting facial fat to reverse volume loss and support facial bones affected by ageing. The treatment not only restores volume but also improves skin quality, making it firmer and more hydrated.

Benefits of Profhilo Structura

  • Natural Look: Developed to maintain facial fat tissues while giving a natural appearance.
  • Long-lasting Results: Offers extended results, reducing the need for frequent touch-ups.
  • No Downtime: Requires no recovery time, allowing patients to resume daily activities immediately.
  • Improves Skin Quality: Enhances skin firmness and hydration alongside its volumizing effects.

Profhilo vs. Profhilo Structura

While both products are developed by IBSA and utilize hyaluronic acid,Profhilo Structura differs from the original Profhilo in several ways:

  • Higher HA Content: Profhilo Structura contains 90 mg/2 mL compared to Profhilo's 64 mg/2 mL.
  • Different Applications: Profhilo acts as an injectable moisturiser and collagen booster, whereas Profhilo Structura targets fat tissue restoration.
  • Injection Techniques: Tailored to target fat tissue regeneration, enhancing midface projection     and reducing hollows and laxity.

Profhilo and Profhilo Structura can be used in separate sessions as a combination treatment, providing optimal results by utilizing the strengths of both injectables.

Clinical Evidence and Launch

Clinical trials of Profhilo Structura have demonstrated impressive outcomes,with 95% of patients noticing significant improvements in the midface area after the first treatment, sustained over three months. This advanced treatment was launched on 4th June in London, marking its European debut nearly a decade after the introduction of the original Profhilo by UK and Ireland distributor HA-Derma.

'Profhilo is a trusted leader in aesthetic medicine,' says Iveta Vinkler,Sales and Marketing Director at HA-Derma. 'While fat often carries negative connotations, it's actually a crucial marker of youth. Our insights into its role in youthful aesthetics are advancing rapidly. The launch of Profhilo Structura equips medical professionals with a natural product tailored to meet the evolving demands of today's discerning aesthetic clients.'


Profhilo Structura is a groundbreaking addition to non-surgical aesthetic procedures, offering a natural and effective method to regain facial volume and shape. Bellezza Clinic London provides both Profhilo and Profhilo Structura treatments, ensuring patients achieve natural results with minimal recovery time. Embrace the future of facial aesthetics with Profhilo Structura, and rediscover a youthful, sculpted appearance.